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KMID : 1024520140230061029
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Journal of the Environmental Sciences
2014 Volume.23 No. 6 p.1029 ~ p.1035
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Influences of Wild Haw (Crataegus pinnatifida BUNGE) on Lowering BUN and Creatinine Concentrations in Dyslipidemia
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Kim Han-Soo
Kim Min-A
Jang Seong-Ho
Cho Han-Jin
Ryu Jae-Young
Kim Sang-Woo
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Abstract
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This study was investigate the influences of wild haw (Crataegus pinnatifida BUNGE) on lowering blood urea nitrogen
(BUN) and creatinine concentrations in dyslipidemic rats. Four groups of rats were fed different diets for 5 weeks:
basal diet (BD group), nondyslipidemic diet+feral haw extract (NDF group), dyslipidemic diet (DLD group), dyslipidemic
diet+feral haw extract (DFH group). BUN, creatinine and uric acid concentrations were significantly higher in the DLD
group than in the BD group. However, DFH group significantly lowered BUN, creatinine and uric acid concentrations
compared to the DLD group. Amylase activity was significantly lower in the DLD group than in the BD group, while
DFH group significantly higher compared to the DLD group. Lipase activity was also also significantly lower in the
DLD group than the other group. Accordingly, these results suggest that haw extract could be effective for improving
kidney function in dyslipidemic rats.
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KEYWORD
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Crataegus pinnatifida BUNGE, BUN, Creatinine, Uric acid, Dyslipidemia
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